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The combination of GLP-1RA and SGLT-2i was found to produce additive cardiovascular benefits compared to either treatment with one agent alone [33]
Researchers continue studying exactly how these drugs protect the heart and exploring their long-term effects
These medications work primarily by enhancing glucose-dependent insulin secretion, suppressing glucagon release when glucose levels are elevated, slowing gastric emptying, and reducing appetite through central nervous system pathways
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