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Doses were administered subcutaneously by the investigator at the clinic, using a prefilled PDS290 pen-injector

This data can be used to monitor trends, identify areas for improvement, and make informed decisions about patient care

Apoptosis, another consequence of oxidative damage and mitochondrial dysfunction, was evaluated using Annexin-V staining, which detects early apoptotic changes by binding to phosphatidylserine exposed on the outer leaflet of the plasma membrane

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This early period is primarily about protocol establishment, tolerance assessment, and getting both compounds into a consistent daily routine