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Prophylactic phenytoin does not improve cerebral edema or survival in acute liver failurea controlled clinical trial

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Lipid Peroxidation: Polyunsaturated fatty acids (PUFAs), especially arachidonic and adrenic acids, are substrates for lipoxygenases (LOX), which drive peroxidation in membrane phospholipids, generating cytotoxic lipid peroxides such as 4-hydroxynonenal (4-HNE) and malondialdehyde (MDA) (Hasan et al., 2023)

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10.1016/S0024-3205(00)00722-0