Mazdutide became the first-ever GLP-1/glucagon dual agonist to receive regulatory approval in June 2025 (China only)
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NOTE: When using this product around the eye area, use fingertips to carefully apply a thin layer (or 1-2 drops) underneath the eyes or on the outside areas of the eye
Pharmacokinetic profiles for the compound place its plasma half-life in the neighborhood of 45 minutes after parenteral administration in animal models, which informs typical dosing intervals in published experiments
Immunocytochemical analysis confirmed that these newly formed spines were functional, showing similar percent correlations with presynaptic markers VGLUT1 and synapsin, and postsynaptic marker, PSD-95, as control-treated neurons