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The peptide works through multiple mechanisms including enhanced angiogenesis (blood vessel formation), increased collagen synthesis, and activation of growth hormone receptors on fibroblasts

For facial skin improvement, topical is often sufficient

Regulatory Toxicology and Pharmacology, 114 , 104665

PMCID: PMC4321783

The study found an increased number of NK cells in the blood and spleen but a decreased amount in the liver tissue of obese rats compared to lean littermates (43)

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