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GLP-1 inhibits intestinal contractions through mechanisms that may involve the central nervous system via vagal pathways or direct action on central receptors [24], as well as the enteric nervous system by modulating neurotransmission through presynaptic receptors affecting nitric oxide release [25,26]
To quickly refresh, semaglutide (the active ingredient in Wegovy) is a GLP-1 receptor agonist that mimics GLP-1, a hormone that helps regulate appetite and blood sugar
Singla-Pareek SL, Kaur C, Kumar B, Pareek A, Sopory SK (2020) Reassessing plant glyoxalases: large family and expanding functions
This can depend on why you're taking semaglutide and how much you're taking
Circ Res 112(2):393405
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