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5.1.2 Effects on pancreatic -cell glucagon release In addition to their insulinotropic effects on -cells, both GIP and GLP-1 play a role in regulating glucagon secretion of pancreatic -cells, with GIP increasing and GLP-1 suppressing glucagon secretion, both in a glucose-dependent manner
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Activation of GHS-R1a phospholipase C IP3 + DAG release of calcium from intracellular stores (endoplasmic reticulum) cytosolic calcium influx fusion of GH vesicles with the membrane exocytosis
Vitamin C: An essential nutrient known for its antioxidant properties
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