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Selective senolytic mechanism distinct from broad cytotoxic agents: Traditional cytotoxic compounds induce apoptosis in proliferating cells without discrimination
Additional Agents The mechanism of action of some drugs remain unknown, but the excellent efficacy of these drugs in the radiosensitization of osteosarcoma deserves our attention
Ageing and certain diseases can lead to depleted levels of Coenzyme Q10 in the body
Critical revision and redrafting: AAS, AG, EP and SMR
One study raised an interesting point: circadian clock-related gene expression may exist in the pituitary, and this expression is related to the expression of GH gene ( CLOCK gene and the BMAL1 gene was not high, which was consistent with the view that different parts of the circadian clock system linked to different functions as circadian oscillators ( CLOCK, PER1, PER2, CRY3, NRLD2 ) showed the difference of expression oscillation in the pituitary of GH transgenic and wild type coho salmon, which indicated that the GH gene might have a regulatory effect on the expression of pituitary clock genes
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