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Specifically, KANKs bind to talin, a cytoskeletal and focal adhesion protein that interacts with the subunit cytoplasmic domains of integrins [1,2,3]
doi:10.1074/jbc.M606192200 Wacker JL, Huang SY, Steele AD, Aron R, Lotz GP, Nguyen Q, Giorgini F, Roberson ED, Lindquist S, Masliah E, Muchowski PJ (2009) Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntingtons disease
The integrative network of circRNA, miRNA and mRNA of epicardial adipose tissue in patients with atrial fibrillation
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