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Nrf 2:INrf2 (Keap1) signaling in oxidative stress

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The condition is commonly asymptomatic, but there may be acute hemolysis crises after taking some drugs, ingesting fava beans, and viral or bacterial infections

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and NETs, in turn, is a known trigger for coagulation and blood vessel occlusion [359], and also involve significant erythrocyte pathologies, specifically related to rheology and oxygen carrying capacity and ultimately resulting in ischemia-reperfusion injury [352]