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A network meta-analysis of 22 randomized controlled trials found that lean mass loss comprises approximately 25% of total weight lost on GLP-1 receptor agonists
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Because of these concerns, the FDA has classified these medications as Pregnancy Category C, meaning potential risks exist, and they should only be used if the benefits outweigh the risks
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GLP-1 receptor agonist added to insulin versus basal-plus or basal-bolus insulin therapy in type 2 diabetes: A systematic review and meta-analysis
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