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Targeting Wnt/-catenin and BCL-2, Two Critical Survival Factors, Synergistically Induces Apoptosis in AML via Rac1-mediated MCL-1 inhibition
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Mechanism appears multifactorial: upregulation of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and synaptic plasticity proteins like synaptophysin
Lipreri da Silva, J
The liver contains a 2-phase detoxification system for managing toxins, hormones, certain pharmaceutical medications, and some herbs
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