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a total of eight signaling pathways overlapped (chemokine signaling, cytokine-cytokine receptor interaction, MAPK signaling, IL-17 signaling, NOD-like receptor signaling, TGF-beta signaling, TNF signaling, and pathways in cancer)

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In contrast to the phosphorylation of ACC2 by AMPK during energy-deficient states, hydroxylation of ACC2 increases under conditions of high glucose content, in particular in skeletal muscle

Nat Rev Clin Oncol 17(7):395417