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If such discomfort does not subside in a reasonable amount of time, contact your doctor

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Weight-Related Comorbidities: These can include conditions such as: Type 2 diabetes High blood pressure (hypertension) High cholesterol (dyslipidemia) Obstructive sleep apnea Cardiovascular disease These criteria are in place because the benefits of these medications in individuals meeting these thresholds generally outweigh the potential risks

In the Phase 3 trials, nausea was reported by approximately 44% of patients on Wegovy (semaglutide 2.4 mg) and approximately 28% of patients on Zepbound (tirzepatide 15 mg) during dose titration, usually mild to moderate, and usually improving with time and dose stabilization

Whether the question is which compound produces superior weight loss, or which suits a specific research protocol, the answer depends on the mechanism, timeline, and regulatory context

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