High-resolution cryo-EM data collection For high-resolution structure determination, data were acquired on Titan Krios G2 and G3i cryo-TEMs (Thermo Fisher Scientific) operated at 300 kV acceleration voltage and equipped with a K3 camera and a BioQuantum energy filter (controlled using Digital Micrograph, version 3.53.41360, all Gatan Inc.)
Next, we investigated the effects of GLP-1RAs on alcohol craving, measured before and after alcohol administration using AUQ
In the further studies, we noted that many other herbal medicines ( Coptis chinensis Franch , Phellodendron amurense , and Berberis sargentiana Schneid , et al.) also reportedly contain some of the same alkaloids compared with FRP (Wang et al., 2009
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