Lab experiments suggest the drug scales up energy production in cartilage
Early clinical studies are promising, but long-term safety, availability, and approval status still matter
Research investigations in aging tissue models demonstrate remarkable improvements across multiple cellular parameters
Simple timing framework Baseline Discuss baseline labs before starting, especially if there is active injury, gut symptoms, infection concern, liver disease, kidney disease, or medication use
First, while our findings remained largely unchanged after excluding participants with comorbid schizophrenia and intellectual disability, and no significant effects of comorbid ADHD or depression were observed on the neurometabolite measures examined, we cannot entirely rule out the potential influence of comorbidities on our results
These data, while revealing that mitophagy can be regulated independently of general ATG, at the same time, outlined a role for cellular redox status in its commitment