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Although the precise mechanisms by which GLP-1 drugs regulate addiction remain unclear, it is thought that they act in a similar way to how they treat obesity, where they act on reward centers of the brain to reduce appetite

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Given the similarities between the brain's and retina's vascular systems, these findings suggest that GLP-1R agonism could also protect the brain's microvasculature, preserving the integrity of the blood-brain barrier and improving cerebral blood flow

Proceedings of the Nutrition Society

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