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Gliptins may represent a valuable alternative to a sulfonylurea or a glitazone after failure of monotherapy with metformin while GLP-1 receptor agonists may be considered as a good alternative to insulin (especially in obese patients) after failure of a dual oral therapy
In contrast, retatrutide, currently in clinical trials, shows even more promise with its triple agonist mechanism, potentially offering enhanced efficacy for those pursuing greater weight loss results
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Families also suffer as they cope with the emotional strain and the demands of caregiving
The short answer is its not a common side effect , but it has been reported in some instances
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