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It should be noted that while the HIF pathway can induce antioxidant genes like SOD2 to maintain adaptive balance under acute hypoxia, this protective effect in chronic diseases like cancer may conversely aid malignant cells in resisting apoptosis, constituting another dimension of intervention complexity [501]
See what research suggests in the Concerns and Cautions section of our article about beetroot juice and supplements
12-month shelf life when properly stored in a sealed container
10.1038/mi.2012.89 21
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started to import the substances and set up their own websites
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