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This reaction has two metabolic consequences: it consumes SAM (the body's universal methyl donor) and it diverts nicotinamide away from the NAD+ salvage pathway

References Kwon Y, et al

These effects occur without elevating IGF-1 or affecting carbohydrate metabolism, differentiating it from full-length HGH in terms of safety and selectivity

If you're taking other medications, keep your healthcare provider informed to avoid any potential interactions