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2.5 mg dose in a 12 mg vial: Target 50 units (0.5 mL)
(2012) 130:e12226
Incretin action in type 2 diabetes: Mechanisms and clinical implications
Use: In combination with a reduced calorie diet and increased physical activity, for the treatment of noncirrhotic MASH with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) Usual Pediatric Dose for Weight Loss 12 YEARS AND OLDER: Wegovy Injection: Initial dose (weeks 1 through 4): 0.25 mg subcutaneously once a week Dose escalation: Weeks 5 through 8: 0.5 mg subcutaneously once a week Weeks 9 through 12: 1 mg subcutaneously once a week Weeks 13 through 16: 1.7 mg subcutaneously once a week Alternatively: 1.7 mg subcutaneously once a week Comments: The recommended maintenance dose is 2.4 mg
This may be counterintuitive, as it seems clear that GLP-1 drugs have overwhelmingly positive effects on kidney function
Manufacturers The drugs have different manufacturers
