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Assistance with administration, reference management and English language provided by E

For safe uses, endotoxin tests with Limulus Amebocyte Lysate (LAL) assays must show levels below 0.01 EU/g

The solution might be to change the medication or add B12 supplements

Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency

Single-use syringes must never be reused

Reported or proposed issue Pregnancy, breastfeeding, children, liver disease, or cancer history Evidence source No direct human safety data Known or theoretical