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Accumulation of -syn as intracellular filamentous aggregates is a pathological feature of both sporadic and familial PD (Goedert et al., 2013)
The Central Drugs Standard Control Organisation (CDSCO) has approved its use for diabetes, but the obesity indication is still under review
Some people have taken unofficial versions regardless, drawn by the promise of rapid weight loss, and it is largely from this group that reports of shedding have surfaced
While animal studies consistently show promising results, human clinical data remains limited
Both have been on the FDAs drug shortage list since 2022
Something that we see is that they help modulate the immune system
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