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Retatrutide may show different patterns given its unique mechanism, but assuming similar regain risk encourages developing sustainable lifestyle modifications during treatment

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doi: 10.1007/s40261-020-00942-2 160 CenaHChiovatoLNappiRE

CASTOR1/2 can form either a CASTOR1 homodimer or CASTOR1/2 heterodimer to inhibit mTORC1 activity

Compensatory hyperphagia and concurrent diuretic therapy were some of the main explanations that were suggested in order to justify this finding