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When IGF-IR is deleted in mature osteoblasts, using OCN promoter-driven Cre line, the KO mice produce less trabecular bone, with an increased proportion of osteoid in the bone, indicating impaired mineralizing functions in OCN IGF-IR / osteoblasts (58,59)
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10.1002/biof.1476 Biofactors
Despite the potential impact of caviar/roe products on the modern international food market, few studies have described the variability of biochemical makeup among different types of fish roe employing single class analysis, namely lipids or proteins rather than the full metabolomic mapping in the analysis of fish roe 12,13
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