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The assay mix, containing Assay Loading Reagent (Fluidigm), DNA Suspension Buffer (Teknova), and combined forward and reverse primers, was loaded into the assay inlets of the IFC
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The SELECT cardiovascular outcomes trial published in 2023 added a cardiovascular benefit signal: semaglutide reduced major adverse cardiovascular events by 20% in overweight and obese patients with established cardiovascular disease, independent of diabetes status
Oral absorption in humans is unproven, but animal studies suggest possible systemic effects even with oral dosing6
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