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421 However, neurophysiological measurements, molecular pathways, and pathological findings do not fully explain the presence of neuropathic pain in diabetes

Its had some effect. Antioxidants such as glutathione are found in a diet rich in fruits and vegetables as well as fish, such as salmon, which has omega-3 fatty acids

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The central clinical idea: when mitochondrial ATP production falls and oxidative stress rises, the brain may lose the energy and antioxidant reserve needed to regulate neurotransmission, maintain cell membranes, recycle methionine, produce SAM, clear adenosine and homocysteine, build glutathione and tolerate medications or supplements

Roostaei T, Sahraian MA, Hajeaghaee S et al (2015) Impact of melatonin on motor, cognitive and neuroimaging indices in patients with multiple sclerosis