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For the majority of the analyses, only the placebo and semaglutide 2.4 mg arms from the STEP 2 trial were analyzed ( n = 395)
Orforglipron , 35
People taking placebo in the study (not on medicine) lost an average of ~2.5% body weight (or about 6 lb)
Drinking more water addresses the dehydration component but does not reverse receptor desensitization in salivary glands
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