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Of interest, early-life exposure to riboflavin-producing commensals has been shown to promote the correct development of the gut and skin MAIT cell response in germ-free murine neonates primed with a synthetic early-life gut microbial community consisting of two Lactobacillaceae , two Enterobacteriaceae and Enterococcus faecalis and the skin commensal Staphylococcus epidermidis, respectively 200,201

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Remarkably, the combination of these drugs induced ferroptosis and significant cell death in p53-mutated hypopharyngeal squamous cell carcinoma

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