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These endogenous primary antioxidants have high catalytic properties but, because the majority are mineral-dependent enzymes, their activity (reduced or enhanced) is directly affected by dietary intake

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The inhibition of MM growth was additionally seen when co-culturing the cancer cells with human HS-5 stromal cells using a transwell model, further showing the compounds potent effect even in conditions mimicking the bone marrow microenvironment (Rogers et al., 2020)

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**RDA not established

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Recombinant human IGF-1 infusions over several hours led to lower protein breakdown and leucine oxidation rates

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