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Are the side effects worse with tirzepatide
Hetrick SE, McKenzie JE, Bailey AP, Sharma V, Moller CI, Badcock PB, et al
Diabetes 58 , 22582266 (2009)
A comprehensive literature search was performed in PubMed, Web of Science, Embase, and Scopus from inception to October 2025 using the keywords tirzepatide, GLP-1/GIP receptor agonist, obstructive sleep apnea, and obesity. Priority was given to randomized controlled trials, major observational studies, and relevant mechanistic research
While the exclusion of weight management treatment may limit reimbursement of GLP-1s, non-obesity/overweight diseases such as diabetes mellitus and certain cardiovascular conditions may be eligible for reimbursement because these indications are not excluded
That does not mean BPC-157 has no role around painful joints
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