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Elevated cortisol directly inhibits GH receptor signaling in target tissues and increases hepatic GH resistance, meaning even if you achieve a GH pulse, downstream IGF-1 production and metabolic signaling are impaired
Among people who stayed on it and reached the full dose, average weight loss was 16.6%
Insurance coverage can offset this, but coverage for weight loss medications remains inconsistent
Lim C, Klesius PH, Shoemaker CA (2001) Dietary iron and fish health
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