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10,18 Finally, the fourth prespecified subgroup included trials in which ALC, when administered in combination with another active agent, was compared with placebo (n=2)
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Moreover, female GM mice exhibited clear muscle hypertrophy, and although male GM mice exhibited a similar trend toward increased muscle weight and muscle hypertrophy, the differences were not statistically significant
Related impurities in peptide medicines
Somapacitan (Sogroya), a long-acting GH analog approved in 2020, requires only once-weekly injection and demonstrated non-inferiority to daily somatropin in the REAL 1 trial (N=136) [19]