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It may mean the body has adapted, the dose needs review, nutrition needs adjustment, strength training needs more support or another metabolic factor is involved

A lower starting dose helps reduce the risk of gastrointestinal side effects such as nausea, vomiting, and diarrhea during the early weeks of treatment

The key distinction is that conventional treatments primarily target hormonal pathways (suppressing estrogen), while GLP-1 agonists target inflammatory and metabolic pathways

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Nuts and seeds, particularly walnuts and flaxseed oil, are additional sources of omega-3 fatty acids (Psota 2006)

5 Conclusion Cisplatin is a highly effective and broad-spectrum anticancer drug, but its severe ototoxicity limits its clinical application, and its mechanism involves various pathways such as DNA damage, oxidative stress, inflammatory response, mitochondrial dysfunction, and ferroptosis