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Both medications are taken as once-weekly subcutaneous injections and work best alongside a reduced-calorie diet and regular physical activity

Months 3-6: Long-Term Optimization Users who cycle properly (8 weeks on, 8 weeks off, or similar) and maintain the protocol through multiple cycles report compounding benefits

These combinations can optimise growth hormone levels and other hormones, supporting overall hormone optimization and performance

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258 Lean muscle mass loss Sarcopenia (loss of muscle strength, mass and function) can be exacerbated by chronic comorbidities, including CVD, and is associated with faster disease progression and higher mortality in these groups