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Glutathione is involved in detoxification, it binds to toxins, such as heavy metals, solvents, and pesticides, and transforms them into a form that can be excreted in urine or bile

Although, any study has not related the viral infection, GSH intracellular levels, and excitotoxic neurodegeneration, the literature suggested that antioxidant responses can prevent the neuron death directly or indirectly

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The virus directly damages host cellular structural proteins and membrane lipid structures, and triggers a cytokine storm leading to immune dysregulation and hyperinflammatory responses, collectively contributing to a range of clinical manifestations ( The diverse pathologies arising from SARS-CoV-2 infection of the reproductive system, while clinically heterogeneous, share a common regulatory axis in their underlying ferroptosis mechanisms, alongside tissue-specific variations