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While sommarutide is undoubtedly an exciting potential treatment option, there is still a lack of clear clinical data on the mechanism of action of GLP-1 agonists in NASH, such as whether GLP-1 agonists have a direct, independent role in improving NASH, or simply by improving body weight, insulin resistance, and so on

Eur Rev Med Pharmacol Sci (2017) 21(2 Suppl):3642

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It even seems to have an anti-inflammatory effect on the body, although more study is needed to confirm this

Wang G-E, Li Y-F, Zhai Y-J, Gong L, Tian J-Y, Hong M, et al

In the 1980s Joel Habener described a new glucagon-related peptide encoded in the anglerfish preproglucagon cDNA