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Macdonald JB, Macdonald B, Golitz LE, LoRusso P, Sekulic A
If you have a BMI of 30 or higher and have at least one weight-related health condition, you may be suitable for semaglutide GLP-1 weight loss treatment
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Ethical approval Not applicable (no original data)
These considerations suggest that GLP-1RA biology is best interpreted within a broader metabolic context in which substrate availability, redox buffering capacity, and tissue-specific energetic constraints shape systemic adaptation to sustained pharmacological weight reduction
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