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Berberine could be the solution
YA: Writing original draft
Peripheral vasculopathy, including Raynauds phenomenon (reduced blood flow in the fingers and toes)
1 The receptors have complementary distribution and activities
Moreover, SCFAs, dose-dependently, which effects dependent on the specific SCFA, segment of the colon animal species and experimental models, may impact IBS-D with increased transit rate
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