Available to buy in the UK from Peptides Lab UK, 5-Amino-1MQ is one of the most extensively characterised selective NNMT inhibitors in current metabolic research, with published pre-clinical evidence spanning adipocyte biology, diet-induced obesity models, NAD+/SAM pathway studies, skeletal muscle function research, and cancer cell biology
As part of our wide range of health services, we offer B12 injections at Noble Clinic
If you have symptoms of deficiency that have never been investigated, see your GP for a blood test before booking any injection
Blocks NNMT in fat cells In 3T3-L1 mouse fat cells, 30 M of 5-Amino-1MQ for 24 hours strongly lowered 1-MNA levels direct proof of NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)
All natural lipotropic B12 injections show no signs of side effects other than possible irritation of injection site
Safety and evidence level: what is and isnt known In the mouse obesity study, systemic administration of the NNMT inhibitor reduced body weight, white-adipose mass and plasma cholesterol without changing food intake and without any observable adverse effects over the study period