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Gorman DM, Liu R, Engberg S, et al
These may include nausea, vomiting, diarrhea, constipation, abdominal discomfort, decreased appetite, or indigestion
Mitochondrial iron overload plays a significant role in promoting PDAC tumorigenesis
Glutathione works by protect energy-producing factories inside cells called mitochondria. Antioxidants are molecules that inhibit other molecules from going through oxidation, a chemical reaction that produces toxins called free radicals
Clinical research further reinforces the beneficial effects of GLP-1RAs on DPN
The data generated during this phase help define the dose range that may be explored in subsequent studies and contribute to understanding exposure-response relationships, pharmacokinetic behavior and safety considerations associated with the investigational compound
