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Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit

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New England Journal of Medicine (2025) The REDEFINE 2 Phase 3 trial evaluated CagriSema in 1,206 adults with overweight or obesity and type 2 diabetes in a 68-week, double-blind, placebo-controlled design

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In addition, ferroptosis in cardiomyocytes also occurred in doxorubicin (DOX)-induced cardiotoxic mice model