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Annals of the New York Academy of Sciences , 1033 , 116

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In infections by Schistosoma mansoni , the sigma class 28-kDa GST (Sm28GST) is crucial in modulating the immune inflammatory response by producing prostaglandin D2 (PGD2), which inhibits the migration of Langerhans cells to the epidermis and leads to the accumulation of dendritic cells in the lymph nodes, which enhances the immune response [15]

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