Unlike L-Carnitine, which has a single, clearly defined role, fat burners combine compounds that elevate thermogenesis, suppress appetite, increase energy expenditure, and enhance focus during a caloric deficit
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Specifically, it promotes HCC cell pyroptosis by ameliorating GM, primarily through increasing the beneficial bacterium Akkermansia muciniphila and reducing harmful bacteria such as Prevotellaceae and Porphyromonadaceae, thereby elevating metabolites like indole and ursolic acid while decreasing metabolites such as betaine and DL-carnitine [193]
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