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They propose based on rodent and monkey studies that this kind of molecule, when administered at high enough doses, may result in weight loss comparable to the weight loss seen with drugs that include GLP-1 as a target, and without the tolerability issues like nausea and vomiting that often come with the approved treatments, according to a peer-reviewed draft paper published this week

It was approved by the FDA for type 2 diabetes in 2010 and for chronic weight management in 2014

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Following a "low and slow" approach starting with a small dose and gradually increasing it allows the digestive system to adapt and significantly reduces discomfort

Employment contracts, workplace policies, or codes of conduct could prohibit substances beyond what appears on drug tests