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One theory is that semaglutide helps to reduce appetite by mimicking the effects of GLP-1

A systematic review of 194 publications identified 42 cases of EDKA associated with perioperative use of SGLT2 inhibitors [16]

Anderson JE

In addition to taking either semaglutide or placebo for the trial, all participants also received standard of care treatment for cardiovascular disease, such as cholesterol modifying medications, antiplatelet therapies, beta blockers or other treatments

Taylor et al., 2021)

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