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The most commonly used drugs are aminosalicylates, corticosteroids (CS), immunomodulators (for example, thiopurines (TPs), methotrexate (MTX), calcineurin inhibitors, Janus kinase (JAK) inhibitors) and biologics drugs
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This is used for several purposes, making: Cysteine - which can be used to make sulfate, glutathione or taurine, or Ammonia - a potential toxin, that is excreted via the urea cycle, or Alpha ketobutyrate SNPs in CBS are often up-regulated
doi: 10.3390/molecules23061297 180
5b) resulted in decreased expression of CYP27A1, CYP27B1, and VDR
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