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Genetic variations in dopamine receptors, appetite-regulatory peptide systems, and lipid metabolism influence how well each medication may work for an individual
L-Carnitine and its amino acid derivative Acetyl-l-Carnitine (ALCAR) may assist with fat-burning activities within cells
Rosen ED, Hsu CH, Wang X, Sakai S, Freeman MW, Gonzalez FJ, Spiegelman BM: C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway
These drugs mimic the action of a natural hormone in the body that regulates appetite and food intake
This is mechanistically consistent with why they might reduce binge eating: they appear to quiet the compulsive, reward-driven relationship with food that characterizes binge eating disorder
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