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Additionally, metabolites such as lactate bidirectionally regulate macrophage polarization stability through epigenetic modifications like H3K18 lactylation, yet their dominant effects and functional thresholds within specific microenvironments remain largely unknown
2024;41(7):e15319
Provides essential components for normal cell and brain function Lowers cholesterol levels
50 KimW.EganJ
2) [13, 14], dispelling the common notion that injectable therapies are a last resort or restricted only to those individuals who fail to respond to maximal doses of oral agents
These mechanistic perspectives provide potential explanations for some of the clinical improvements seen and illustrate the various pathways through which FMT might exert its effects on disease processes
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