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The MHRA-approved Summaries of Product Characteristics (SmPCs) for semaglutide, liraglutide and tirzepatide do not list infertility as a recognised adverse effect, though clinical trials were not specifically designed to detect fertility issues

As specialists point out, the medications ability to imitate GLP-1 hormone functions is crucial for appetite control, making it a valuable tool for those seeking long-term management of their body composition

The ISSA GLP-1 Weight Loss Support Training course equips fitness and wellness professionals to understand these medications, adapt training safely, and coach sustainable behavior change, without overstepping scope of practice

Narration: And I found myself around 320 pounds and tried a lot of different diets, and I got myself down to about 215 pounds

These factors contribute to the high prevalence of obesity but are not fully addressed in existing tirzepatide trials

Constipation, bloating, or irregular bowel movements